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CBD safety & quality

CBD is generally well-tolerated, but not every product on the shelf is created equal. Here's what to check.

A printed laboratory analysis report beside a small amber glass dropper bottle and a sprig of hemp on a bright countertop

Possible side effects

  • Drowsiness, especially at higher doses
  • Dry mouth
  • Reduced appetite or upset stomach
  • Occasional diarrhea at very high doses

Drug interactions to know

CBD can raise or lower blood levels of medications metabolized by the CYP3A4 and CYP2C19 liver enzymes. Common examples include warfarin, some statins, certain anti-seizure medications, and specific antidepressants. Ask your pharmacist.

How to read a Certificate of Analysis (COA)

  • Batch number matches the product label
  • Cannabinoid potency within 10% of what's advertised
  • "Pass" or "non-detected" for pesticides, heavy metals, and solvents
  • Microbial and mycotoxin screening for ingested products
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